nsaid

Unda, these are what i got fr the net....u may comments if any of the points are not correct or accurate..btw, im taking Arcoxia, and yes its a type of nsaid, but the article says its the new generation of nsaid, and the effects slightly differ from the traditional ones, like ibuprofen and diclofenac.

( NSAID - non-steroidal anti-inflammatory drug )

Dyspepsia is a pain or an uncomfortable feeling in the upper middle part of your stomach. The pain might come and go, but it's usually there most of the time. Some medicines, like anti-inflammatory medicines, can cause dyspepsia.......

"NSAIDs work by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in producing prostaglandins, in response to injury or certain diseases. These prostaglandins cause pain, swelling and inflammation. Because NSAIDs block the production of these prostaglandins, they are effective at relieving pain and inflammation.

Cyclo-oxygenase does not only produce prostaglandins that cause inflammation. It also produces prostaglandins that have useful roles in the body. There are two different forms of cyclo-oxygenase, COX-1 and COX-2. COX-2 is the form that (among other things) produces prostaglandins that cause inflammation. COX-1 does not produce inflammatory prostaglandins, but does produce others that have useful effects, including some that are involved in maintaining a healthy stomach and intestinal lining.

Traditional NSAIDs, such as ibuprofen or diclofenac, block the action of both COX-1 and COX-2, and this is why they can sometimes cause side effects such as stomach irritation and peptic ulcers. Etoricoxib belongs to a new generation of NSAIDs that selectively block the action of COX-2. This means that it stops the production of inflammatory prostaglandins, without stopping the production of prostaglandins that protect the stomach and intestines. It therefore reduces pain and inflammation, but is less likely than traditional NSAIDs to cause side effects on the stomach and intestines (although such side effects are still possible)."


my question, if it is really dyspepsia, any chance that it might come again in future? and what about the statement saying that the effects are less likely to cause the stomach pain? i feel a bit hesitated to call up the doc, segan plak rasa hehe, not until u give me the explanation....toche toche!